Posttranslational protein modifications: current implications for cancer detection, prevention, and therapeutics.

@article{Krueger2006PosttranslationalPM,
  title={Posttranslational protein modifications: current implications for cancer detection, prevention, and therapeutics.},
  author={Karl E Krueger and Sudhir Srivastava},
  journal={Molecular & cellular proteomics : MCP},
  year={2006},
  volume={5 10},
  pages={1799-810}
}
Over the last several years major advances in sensitive high throughput technologies have been made in the fields of genomics and proteomics. The hunt for diagnostic and prognostic cancer biomarkers exploits these recent technology platforms. Although the recent developments and use of genomics and proteomics offer much promise in the search for molecular markers of early stage cancers, these methods are inadequate to probe the dynamic nature of signaling processes that cells exhibit during… CONTINUE READING
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Posttranslational Modifications in Cancer Molecular & Cellular Proteomics

  • N. Jessani, M. Humphrey, +7 authors B. F. Cravatt
  • by on O cber 19,
  • 2006

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