Posttranslational modification of protein kinase A. The link between short-term and long-term memory

@article{Spatz1995PosttranslationalMO,
  title={Posttranslational modification of protein kinase A. The link between short-term and long-term memory},
  author={H Spatz},
  journal={Behavioural Brain Research},
  year={1995},
  volume={66},
  pages={79-84}
}
Both for Aplysia and Drosophila a key role in the molecular mechanism of learning and memory processes has been assigned to the cAMP cascade. In any learning process a short-time stimulus has to be translated into long-lasting changes. The molecular correlate must be a cascade of biochemical reactions with different kinetics, functionally interlinked and operating in overlapping time ranges. Biochemical studies in Drosophila have led to the suggestion that one of these steps is a proteolytic… CONTINUE READING

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