Posttranscriptional regulation of 2,4-diacetylphloroglucinol production by GidA and TrmE in Pseudomonas fluorescens 2P24.

@article{Zhang2014PosttranscriptionalRO,
  title={Posttranscriptional regulation of 2,4-diacetylphloroglucinol production by GidA and TrmE in Pseudomonas fluorescens 2P24.},
  author={Wei Zhang and Zhao Yu-ling Zhao and Bo Zhang and Xiao-Gang Wu and Zheng-Guang Ren and Li-qun Zhang},
  journal={Applied and environmental microbiology},
  year={2014},
  volume={80 13},
  pages={3972-81}
}
Pseudomonas fluorescens 2P24 is a soilborne bacterium that synthesizes and excretes multiple antimicrobial metabolites. The polyketide compound 2,4-diacetylphloroglucinol (2,4-DAPG), synthesized by the phlACBD locus, is its major biocontrol determinant. This study investigated two mutants defective in antagonistic activity against Rhizoctonia solani. Deletion of the gidA (PM701) or trmE (PM702) gene from strain 2P24 completely inhibited the production of 2,4-DAPG and its precursors… CONTINUE READING

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