Posttranscriptional regulation of cytochrome c expression during the developmental cycle of Trypanosoma brucei.

@article{Torri1988PosttranscriptionalRO,
  title={Posttranscriptional regulation of cytochrome c expression during the developmental cycle of Trypanosoma brucei.},
  author={Albert F Torri and Stephen L. Hajduk},
  journal={Molecular and cellular biology},
  year={1988},
  volume={8 11},
  pages={
          4625-33
        }
}
We examined the expression of a nucleus-encoded mitochondrial protein, cytochrome c, during the life cycle of Trypanosoma brucei. The bloodstream forms of T. brucei, the long slender and short stumpy trypanosomes, have inactive mitochondria with no detectable cytochrome-mediated respiration. The insect form of T. brucei, the procyclic trypanosomes, has fully functional mitochondria. Cytochrome c is spectrally undetectable in the bloodstream forms of trypanosomes, but during differentiation to… CONTINUE READING

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