Posttraining intracranial self-stimulation ameliorates the detrimental effects of parafascicular thalamic lesions on active avoidance in young and aged rats.

@article{RedolarRipoll2003PosttrainingIS,
  title={Posttraining intracranial self-stimulation ameliorates the detrimental effects of parafascicular thalamic lesions on active avoidance in young and aged rats.},
  author={Diego Redolar-Ripoll and Carles Soriano-Mas and Gemma Guillazo-Blanch and Laura Aldavert-Vera and Pilar Segura-Torres and Ignacio Morgado-Bernal},
  journal={Behavioral neuroscience},
  year={2003},
  volume={117 2},
  pages={
          246-56
        }
}
To evaluate whether intracranial self-stimulation (SS) ameliorates conditioning deficits induced by parafascicular nucleus (PF) damage in young and aged rats, the authors gave rats a daily session of 2-way active avoidance until a fixed criterion was achieved. Four experimental groups were established in both young and aged rats: SS treatment after every conditioning session (SS groups), pretraining PF lesions (lesion groups), PF lesions and SS treatment (L + SS groups), and controls. SS… CONTINUE READING

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