Postsynaptic enrichment of Eps8 at dendritic shaft synapses of unipolar brush cells in rat cerebellum.

@article{Sekerkov2007PostsynapticEO,
  title={Postsynaptic enrichment of Eps8 at dendritic shaft synapses of unipolar brush cells in rat cerebellum.},
  author={Gabriella Sekerkov{\'a} and Maria R. Di{\~n}o and Ema Iliji{\'c} and Matthew Russo and L Zheng and James R. Bartles and Enrico Mugnaini},
  journal={Neuroscience},
  year={2007},
  volume={145 1},
  pages={116-29}
}
Epidermal growth factor receptor pathway substrate 8 (Eps8) is a widely expressed multidomain signaling protein that coordinates two disparate GTPase-dependent mechanisms: actin reorganization via Ras/Rac pathways and receptor trafficking via Rab5. Expression of Eps8, the gene encoding the founding member of the Eps8 family of proteins, was found in cerebellum by virtual Northern analysis and in situ hybridization. Because the cerebellum has a well-known cellular architecture and is a favored… CONTINUE READING
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