Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons.

@article{Ferreira1996PostsynapticEC,
  title={Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons.},
  author={Ana C{\'a}ssia S Ferreira and Leyi Li and Lih Shen Chin and Paul Greengard and Kenneth S. Kosik},
  journal={Molecular and cellular neurosciences},
  year={1996},
  volume={8 4},
  pages={286-99}
}
In a previous study, we reported a retardation in process outgrowth and synapse formation in cultured hippocampal neurons from synapsin I-deficient mice. Here we investigated whether this delay in synaptogenesis was attributable to pre- or postsynaptic elements. The experimental paradigm used in this study involved the establishment of heterochronic cocultures of neurons from wild-type and synapsin I-deficient neurons established synapses with mature wild-type postsynaptic elements after 24 and… CONTINUE READING

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