Postsynaptic complex spike bursting enables the induction of LTP by theta frequency synaptic stimulation.

@article{Thomas1998PostsynapticCS,
  title={Postsynaptic complex spike bursting enables the induction of LTP by theta frequency synaptic stimulation.},
  author={M. J. -Andr{\'e} Thomas and Ayako Miyamori Watabe and Teena D. Moody and Michael Makhinson and Thomas J O'Dell},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1998},
  volume={18 18},
  pages={7118-26}
}
Long-term potentiation (LTP), a persistent enhancement of synaptic transmission that may be involved in some forms of learning and memory, is induced at excitatory synapses in the CA1 region of the hippocampus by coincident presynaptic and postsynaptic activity. Although action potentials back-propagating into dendrites of hippocampal pyramidal cells provide sufficient postsynaptic activity to induce LTP under some in vitro conditions, it is not known whether LTP can be induced by patterns of… CONTINUE READING
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Voltagegated Ca 21 channel blockers, v-AgaIVA and Ni 21, suppress the induction of theta-burst induced long-term potentiation in guinea-pig hippocampal CA1

  • K-I Ito, M Miura, +8 authors H Miyakawa
  • 1995
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