Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus.

@article{Henneberger2002PostsynapticAO,
  title={Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus.},
  author={Christian Henneberger and Ren{\'e} J{\"u}ttner and Thom{\'a}s Rothe and Rosemarie Grantyn},
  journal={Journal of neurophysiology},
  year={2002},
  volume={88 2},
  pages={
          595-603
        }
}
The neurotrophin brain-derived neurotrophic factor (BDNF) is involved in numerous aspects of synapse development and plasticity. The present study was aimed at clarifying the significance of endogenous BDNF for the synaptically driven spontaneous network activity and GABAergic inhibition in the superficial layers of the mouse superior colliculus. In this structure neuron survival is unaffected by the absence of BDNF. Two experimental approaches were used: comparison of BDNF-deficient (-/-) and… CONTINUE READING

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