Postprandial changes in serum concentrations of gastrin-17, gastrin-34, and total gastrin in patients with duodenal or gastric ulcers and in normal subjects.

@article{Walker1985PostprandialCI,
  title={Postprandial changes in serum concentrations of gastrin-17, gastrin-34, and total gastrin in patients with duodenal or gastric ulcers and in normal subjects.},
  author={K. E. Walker and B R Pinchbeck and Varocha Mahachai and I. H. Simpson and P. Kirdeikis and Lori Zuk and K. Brunet and Richard Sherbaniuk and L Chitnuyanondh and Robert Cherry},
  journal={Clinical therapeutics},
  year={1985},
  volume={7 6},
  pages={704-16}
}
The fasting concentrations of total gastrin and gastrin-17 (G-17) were similar in healthy volunteers and in asymptomatic patients with gastric ulcers or duodenal ulcers. However, the fasting serum concentration of gastrin-34 (G-34) was higher in patients with gastric ulcers than in normal subjects, in whom it was higher than in patients with duodenal ulcers. In response to food, the increases in G-17, G-34, and total gastrin were greater in ulcer patients than in healthy subjects. Cimetidine… CONTINUE READING