Postprandial VLDL lipolysis products increase monocyte adhesion and lipid droplet formation via activation of ERK2 and NFκB.

@article{Hartigh2014PostprandialVL,
  title={Postprandial VLDL lipolysis products increase monocyte adhesion and lipid droplet formation via activation of ERK2 and NFκB.},
  author={Laura J den Hartigh and Robin Altman and Jennifer E Norman and John C. Rutledge},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2014},
  volume={306 1},
  pages={H109-20}
}
Postprandial lipemia is characterized by a transient increase in circulating triglyceride-rich lipoproteins such as very low-density lipoprotein (VLDL) and has been shown to activate monocytes in vivo. Lipolysis of VLDL releases remnant particles, phospholipids, monoglycerides, diglycerides, and fatty acids in close proximity to endothelial cells and monocytes. We hypothesized that postprandial VLDL lipolysis products could activate and recruit monocytes by increasing monocyte expression of… CONTINUE READING