Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy.

@article{Paredes2010PostpartumAD,
  title={Postpartum antiretroviral drug resistance in HIV-1-infected women receiving pregnancy-limited antiretroviral therapy.},
  author={Roger Paredes and Irene Cheng and Daniel R. Kuritzkes and Ruth E Tuomala},
  journal={AIDS},
  year={2010},
  volume={24 1},
  pages={45-53}
}
BACKGROUND Pregnancy-limited antiretroviral therapy (PLAT) drastically reduces HIV-1 transmission to the newborn, but may select for antiretroviral drug resistance mutations in mothers. METHODS We evaluated antiretroviral-naive, HIV-1-infected pregnant women who received PLAT between 1998 and 2005, and had 2-month or 6-month postpartum plasma samples available with HIV-1 RNA levels more than 500 copies/ml. Postpartum drug resistance mutation rates were assessed blindly using population… CONTINUE READING
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