Postorgasmic Illness Syndrome: Two Cases

@article{Waldinger2002PostorgasmicIS,
  title={Postorgasmic Illness Syndrome: Two Cases},
  author={Marcel D. Waldinger and Dave Henri Schweitzer},
  journal={Journal of Sex \& Marital Therapy},
  year={2002},
  volume={28},
  pages={251 - 255}
}
We describe the symptoms of a postejaculatory syndrome in two men with spontaneous ejaculations. The syndrome consists of severe fatigue, intense warmth, and a flulike state, with generalized myalgia. These symptoms occur rapidly after ejaculation and only disappear after 4 to 7 days. The symptoms are so severe that sexual activity is avoided. The cluster of symptoms is named postorgasmic illness syndrome (POIS). To date, no explanation has been offered for the etiology and pathogenesis of the… 
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55 Citations

Post-orgasmic illness syndrome: history and current perspectives.

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The clinical assessment and differentiation of the diagnosis was difficult and consisted in several clinical criteria, a functional test and allergy valuation, and the combination of symptoms and pathophysiological mechanisms pointed to other sex related allergies, such as seminal plasma protein allergy.

Preejaculatory illness syndrome: Two cases of a rare psychosomatic disorder

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Two cases of preejaculatory illness syndrome are presented, which shared common symptoms of sympathetic over activity, the sensation of impending death, and muscle atonia with subsequent failure to ejaculate.

Post-orgasmic Illness Syndrome

TLDR
The common symptoms of Post-orgasmic illness syndrome include cognitive disturbance, fatigue, memory and concentration issues, and sometimes flulike symptoms such as rhinitis, nasal congestion, and myalgia.

Post orgasmic illness syndrome successfully managed with antihistamine: A case report

Post-Orgasmic Illness Syndrome: A Review.

Clinical experience with post-orgasmic illness syndrome (POIS) patients—characteristics and possible treatment modality

  • Y. Reisman
  • Medicine, Psychology
    International Journal of Impotence Research
  • 2020
TLDR
A series of 14 highly selected patients who were actively looking for medical help as POIS has a significant effect on patients and their partners are described, to increase knowledge about this syndrome and possible treatment modality.

Successful treatment of Post-orgasmic illness syndrome with human chorionic gonadotropin

The first Tunisian case of postorgasmic illness syndrome: A case report

TLDR
Through a clinical observation, the first case diagnosed in Tunisia is illustrated and the difficulties in the etiological diagnosis and the therapeutic management of this syndrome are illustrated.

Post-orgasmic Illness Syndrome: A Closer Look

TLDR
This syndrome still needs more research to understand its mechanisms to obtain clearer treatment, and the clinician's awareness is needed to recognize this syndrome so that it is not misdiagnosed.
...

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