Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911).

@article{Bolla2005PostoperativeRA,
  title={Postoperative radiotherapy after radical prostatectomy: a randomised controlled trial (EORTC trial 22911).},
  author={Michel Bolla and Hendrik van Poppel and Laurence Collette and Paul van Cangh and Kris Vekemans and Luigi Filippo Da Pozzo and T M de Reijke and Antony C Verbaeys and J P Bosset and Roland F P van Velthoven and J. Marechal and Pierre G M Scalliet and Karin Haustermans and Marianne Pi{\'e}rart},
  journal={Lancet},
  year={2005},
  volume={366 9485},
  pages={572-8}
}
BACKGROUND Local failure after prostatectomy can arise in patients with cancer extending beyond the capsule. We did a randomised controlled trial to compare radical prostatectomy followed by immediate external irradiation with prostatectomy alone for patients with positive surgical margin or pT3 prostate cancer. METHODS After undergoing radical retropubic prostatectomy, 503 patients were randomly assigned to a wait-and-see policy, and 502 to immediate postoperative radiotherapy (60 Gy… CONTINUE READING
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