Postoperative pain management by intranasal demand-adapted fentanyl titration.

@article{Striebel1992PostoperativePM,
  title={Postoperative pain management by intranasal demand-adapted fentanyl titration.},
  author={H. W. Striebel and D I Koenigs and J. A. Kr{\"a}mer},
  journal={Anesthesiology},
  year={1992},
  volume={77 2},
  pages={281-5}
}
The aim of the present study was to investigate whether intranasal administration of fentanyl allows a demand-adapted postoperative opioid titration. Forty-two patients who had undergone surgery for lumbar intervertebral disk protrusion were included in a prospective randomized double-blind study. When complaining about intense pain, 22 patients received six sprays of fentanyl (0.027 mg) intranasally and 6 ml sodium chloride 0.9% intravenously and 20 patients received six sprays of sodium… CONTINUE READING

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