Postoperative opioid analgesia: time for a reconsideration?

  title={Postoperative opioid analgesia: time for a reconsideration?},
  author={Henrik Kehlet and G W Rung and Torben Callesen},
  journal={Journal of clinical anesthesia},
  volume={8 6},
Postoperative pain relief has improved in recent years with the development of new analgesics, additional routes of administration and the appearance of the hypothesis of preemptive as well as balanced analgesia (Kehlet H; Postoperative pain relief-what is the issue? Br J Anaesth 1994;72:375-8). Many initial improvements simply involved the administration of opioid analgesics in new ways, such as continuous or on demand intravenous (i.v.) or epidural infusion. These methods allow lower total… CONTINUE READING

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