Postoperative concomitant irradiation and chemotherapy with mitomycin C and bleomycin for advanced head-and-neck carcinoma.

@article{mid2003PostoperativeCI,
  title={Postoperative concomitant irradiation and chemotherapy with mitomycin C and bleomycin for advanced head-and-neck carcinoma.},
  author={Lojze {\vS}mid and Marjan Budihna and Branko Zakotnik and Erika Soba and Primo{\vz} Strojan and Igor Fajdiga and Miha Žargi and Irena Oblak and Marta Dremelj and Hotimir Le{\vs}ni{\vc}ar},
  journal={International journal of radiation oncology, biology, physics},
  year={2003},
  volume={56 4},
  pages={1055-62}
}
PURPOSE In a prospective randomized clinical study, simultaneous postoperative application of irradiation (RT), mitomycin C, and bleomycin was tested in a group of patients with operable advanced head-and-neck carcinoma. It was expected that the planned combined postoperative therapy would reduce the number of locoregional recurrences and prolong survival. METHODS AND MATERIALS A total of 114 eligible patients with Stage III or IV squamous cell head-and-neck carcinoma were randomized to… CONTINUE READING

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