Postoperative complications and mortality following colectomy for ulcerative colitis.

@article{deSilva2011PostoperativeCA,
  title={Postoperative complications and mortality following colectomy for ulcerative colitis.},
  author={Shanika de Silva and Christopher Ma and Marie-Claude Proulx and Marcelo Crespin and Belle S. Kaplan and James N. Hubbard and Martin Prusinkiewicz and andrew. fong and Remo Panaccione and Subrata Ghosh and Paul L. Beck and Anthony R. MacLean and Donald Buie and Gilaad G. Kaplan},
  journal={Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association},
  year={2011},
  volume={9 11},
  pages={
          972-80
        }
}
  • S. de SilvaChristopher Ma G. Kaplan
  • Published 1 November 2011
  • Medicine
  • Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association

Postoperative Complications Following Colectomy for Ulcerative Colitis in Children

Colectomy UC was uncommon and rates have remained stable and postcolectomy complications were common, especially in patients undergoing emergent colectomy, which suggests optimizing timing of colectomies may reduce postoperative complications.

Postoperative complications following colectomy for ulcerative colitis: A validation study

Administrative data identified the same risk factors for postoperative complications as chart review, but overestimated the magnitude of risk.

Colectomy with ileostomy for severe ulcerative colitis-postoperative complications and risk factors

Colectomy in high-risk UC patients is associated with significant morbidity, however, most of the surgical complications can be treated conservatively and overall mortality is low.

Mortality Is Rare Following Elective and Non-elective Surgery for Ulcerative Colitis, but Mild Postoperative Complications Are Common

Surgery for UC is not associated with any mortality at 30 days and very low mortality at 90 days, however, surgery is associated with an increased rate of minor postoperative complications and readmissions.

Surgery for ulcerative colitis in geriatric patients is safe with similar risk to younger patients.

Geriatric patients undergoing surgery for UC are not at increased risk of surgery-related morbidity or mortality compared with a younger cohort, and the rates of surgical complications and mortality in patients aged ≥65 years after colectomy for ulcerative colitis are unchanged.

Risk of Colectomy in Patients With Pediatric-onset Ulcerative Colitis

Male sex and higher Pediatric Ulcerative Colitis Activity Index score at diagnosis are independent risk factors for colectomy in children with UC with long-term follow-up.

Trends in Morbidity and Mortality Following Colectomy Among Patients with Ulcerative Colitis in the Biologic Era (2002–2013): A Study Using the National Inpatient Sample

Evaluated temporal trends and treatment outcomes following TAC among hospitalized UC patients in the biologic era found older age, race, emergent admissions and delayed surgery are predictive factors of both postoperative morbidity and mortality.

Clinical Predictors of the Risk of Early Colectomy in Ulcerative Colitis: A Population-based Study

Patients admitted to hospital with UC within 3 years of diagnosis have a high risk of early colectomy, particularly true in middle-aged men, those living in rural areas, and those without response to infliximab.

Decreasing Colectomy Rates for Ulcerative Colitis: A Population-Based Time Trend Study

From 1997 to 2009, use of purine anti-metabolites increased and elective colectomy rates in UC patients decreased significantly and emergent colectomies rates were stable, which may have been due to rapid progression of disease activity.
...

References

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Evaluating postoperative morbidity and mortality using a nationally representative database and determining the factors that influenced outcomes found postoperative mortality was lowest in hospitals that performed the highest volume of operations.

Clinical course during the first 10 years of ulcerative colitis: results from a population-based inception cohort (IBSEN Study)

The prognosis for UC during the first 10 years was generally good, the colectomy rate was low, and a large proportion of patients were in remission as time progressed, suggesting patients with initially extensive colitis and elevated ESR could benefit from an early potent medical treatment strategy.

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The incidence of arterial thromboembolic diseases in inflammatory bowel disease: a population-based study.

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  • Medicine
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
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