Postoperative Nausea and Vomiting and Outcome

  title={Postoperative Nausea and Vomiting and Outcome},
  author={Phillip E. Scuderi and Lydia A. Conlay},
  journal={International Anesthesiology Clinics},
The concept of evidence-based medicine has gained considerable support over the past decade. It is an approach that makes use of a systematic evaluation of the scientific information that is available related to a particular topic or area. There are three components to an evidence-based evaluation. An appropriate question must first be formulated. Because it is the scientific literature that is the foundation for the recommendations in an evidence-based approach to patient management… 

Prevalence of postoperative nausea and vomiting: A systematic review and meta-analysis

Considering the high prevalence of PONV and the goal to better control it, it is necessary to use high cost-effective approaches and recommendations and to educate health caregivers and patients.

What are the risk factors for nausea and vomiting after neurosurgery? A systematic review.

Overall, the methodological quality of the studies was fair, with few studies controlling for confounders and many with limited explanations of how the risk factors and/or outcomes were measured.

Evidence-based analysis of risk factors for postoperative nausea and vomiting.

The most reliable independent predictors of PONV were female gender, history of PonV or motion sickness, non-smoker, younger age, duration of anaesthesia with volatile anaesthetics, and postoperative opioids.

Factors Associated with Discontinuation of Postoperative Intravenous Patient Controlled Analgesia

It is necessary to provide additional medication and nursing interventions to reduce nausea, which is the symptom associated with PCA discontinuation, especially in the operation of female subjects and thyroidectomy under TIVA.

Retracted: Prevention of postoperative vomiting with granisetron in paediatric patients with and without a history of motion sickness.

‘vomiting after paediatric strabismus surgery’, by Fujii Y, Saitoh Y, Tanaka H, and Toyooka H, has been retracted by agreement between the journal Editor, Neil Morton, and Blackwell Publishing Ltd.

Postoperative Nausea and Vomiting in the Plastic Surgery Patient

A prophylactic regimen was identified that demonstrated a decrease in the incidence of PONV from the published incidence of 22% to 3%, and the regimen includes the use of multiple antiemetic agents.

Dexamethasone compared to metoclopramide in the prophylaxis of emesis in children undergoing ambulatory surgical procedures.

BACKGROUND AND OBJECTIVES Postoperative vomiting is a common and unpleasant complication. Currently, however, mathematical models, such as number necessary to treat (NNT) and relative risk reduction

Applicability of Risk Scores for Postoperative Nausea and Vomiting in a Taiwanese Population Undergoing General Anaesthesia

Five popular scoring systems for postoperative nausea and vomiting (PONV) were validated and compared with two new predictive models in a Taiwanese population to show that using female gender as the only predictor of PONV had predictive power with 75% sensitivity and 54% specificity.



Metoclopramide in the prevention of postoperative nausea and vomiting: a quantitative systematic review of randomized, placebo-controlled studies.

There was no evidence of dose-responsiveness with oral, i.m., intranasal or i.v. metoclopramide in children and adults, and there was one adult who experienced extrapyramidal symptoms with metoclobramide.

A quantitative systematic review of ondansetron in treatment of established postoperative nausea and vomiting

Stopping further postoperative nausea and vomiting in 25% of the patients may be the best that can be achieved currently and a false impression of ondansetron's efficacy may arise because a quarter of all relevant published reports are duplicates, and reporting of study results is uncritical.

5-HT3 receptor antagonistsvs traditional agents for the prophylaxis of postoperative nausea and vomiting

The reduction in the odds of PONV and vomiting is significant in the overall analysis and the subgroup analyses comparing 5-HT3 receptor antagonists with droperidol and metoclopramide.

5-HT3 receptor antagonists vs traditional agents for the prophylaxis of postoperative nausea and vomiting.

The reduction in the odds of PONV and vomiting is significant in the overall analysis and the subgroup analyses comparing 5-HT3 receptor antagonists with droperidol and metoclopramide.

Comparative efficacy and safety of ondansetron, droperidol, and metoclopramide for preventing postoperative nausea and vomiting: a meta-analysis.

Ondansetron and droperidol were more effective than metoclopramide in reducing postoperative vomiting and the overall risk of adverse effects did not differ.

Cost-effectiveness of Prophylactic Antiemetic Therapy with Ondansetron, Droperidol, or Placebo

The use of prophylactic antiemetic therapy in high-risk ambulatory surgical patients was more effective in preventing PONV and achieved greater patient satisfaction at a lower cost compared with placebo.

Evidence-based medicine.

  • K. H. Lee
  • Medicine
    Singapore medical journal
  • 1997
Evidence based-medicine has developed as a tool whose purpose is to help physicians keep up to date, expand their knowledge, and improve clinical practice and studies suggest that practicing EBM might prevent the unnecessary expense of potentially inadequate prescriptions, promote critical thinking, identify and stimulate good practices, and eliminate those that are ineffective or harmful.

Efficacy, Dose‐Response, and Safety of Ondansetron in Prevention of Postoperative Nausea and Vomiting: A Quantitative Systematic Review of Randomized Placebo‐controlled Trials

If the risk of PONV is very high, for every 100 patients receiving an adequate dose of ondansetron 20 patients will not vomit and three will have a headache who would not have had these adverse effects without the drug.

A survey of postoperative nausea and vomiting

The most important predictive factors associated with an increased risk for nausea and vomiting were female gender, a previous history of postoperative sickness, a longer duration of surgery, nonsmoking and a history of motion sickness.

Users' guides to the medical literature: XIV. How to decide on the applicability of clinical trial results to your patient. Evidence-Based Medicine Working Group.

The attending physician on duty when a poor, 45-year-old man presents to the emergency department of a general hospital in the Philippines has severe chest pain for 2 hours, associated with clammy perspiration, and decides whether to offer this patient a thrombolytic agent.