Postnatal regulation of myosin heavy chain isoform expression and metabolic enzyme activity by nutrition.

  title={Postnatal regulation of myosin heavy chain isoform expression and metabolic enzyme activity by nutrition.},
  author={Peter White and Dario Cattaneo and Margaret Joy Dauncey},
  journal={The British journal of nutrition},
  volume={84 2},
Development of muscle is critically dependent on several hormones which in turn are regulated by nutritional status. We therefore determined the impact of mild postnatal undernutrition on key markers of myofibre function: type I slow myosin heavy chain (MyHC) isoform, myosin ATPase, succinate dehydrogenase and alpha-glycerophosphate dehydrogenase. In situ hybridization, immunocytochemistry and enzyme histochemistry were used to assess functionally distinct muscles from 6-week-old pigs which had… CONTINUE READING


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