Postnatal maturation of the hyperpolarization-activated cation current, I(h), in trigeminal sensory neurons.

@article{Cho2011PostnatalMO,
  title={Postnatal maturation of the hyperpolarization-activated cation current, I(h), in trigeminal sensory neurons.},
  author={Hyun-jung Cho and John B. Furness and Ernest A. Jennings},
  journal={Journal of neurophysiology},
  year={2011},
  volume={106 4},
  pages={2045-56}
}
Hyperpolarization-activated inward currents (I(h)) contribute to neuronal excitability in sensory neurons. Four subtypes of hyperpolarization-activated cyclic nucleotide-gated (HCN) channels generate I(h), with different activation kinetics and cAMP sensitivities. The aim of the present study was to examine the postnatal development of I(h) and HCN channel subunits in trigeminal ganglion (TG) neurons. I(h) was investigated in acutely dissociated TG neurons from rats aged between postnatal day… CONTINUE READING