Postnatal innervation of the rat superior colliculus by axons of late-born retinal ganglion cells.

@article{Dallimore2002PostnatalIO,
  title={Postnatal innervation of the rat superior colliculus by axons of late-born retinal ganglion cells.},
  author={Elizabeth J Dallimore and Qi Qi Cui and Lyn Beazley and Alan R Harvey},
  journal={The European journal of neuroscience},
  year={2002},
  volume={16 7},
  pages={1295-304}
}
Rat retinal ganglion cells (RGCs) are generated between embryonic day (E) 13 and E19. Retinal axons first reach the superior colliculus at E16/16.5 but the time of arrival of axons from late-born RGCs is unknown. This study examined (i) whether there is a correlation between RGC genesis and the timing of retinotectal innervation and (ii) when axons of late-born RGCs reach the superior colliculus. Pregnant Wistar rats were injected intraperitoneally with bromodeoxyuridine (BrdU) on E16, E18 or… CONTINUE READING