Postnatal growth, differentiation, and aging of the mouse intervertebral disc.

@article{Dahia2009PostnatalGD,
  title={Postnatal growth, differentiation, and aging of the mouse intervertebral disc.},
  author={Chitra Lekha Dahia and Eric J. Mahoney and Atiq A Durrani and Christopher C. Wylie},
  journal={Spine},
  year={2009},
  volume={34 5},
  pages={447-55}
}
STUDY DESIGN This study follows postnatal intervertebral disc (IVD) growth and differentiation in the mouse. OBJECTIVE.: To initiate use of the mouse as a model system for postnatal IVD differentiation and growth, and to serve as a basis for assaying changes caused by disease or genetic or experimental perturbation. SUMMARY OF BACKGROUND DATA Lower back pain caused by disc degeneration is one of the most common clinical conditions worldwide. There is currently no completely effective… CONTINUE READING