Postnatal exposure to MK801 induces selective changes in GAD67 or parvalbumin

@article{Turner2009PostnatalET,
  title={Postnatal exposure to MK801 induces selective changes in GAD67 or parvalbumin},
  author={Christopher Paul Turner and Danielle Debenedetto and Emily J Ware and Robert C Stowe and Andrew W Lee and John P. Swanson and Caroline Walburg and Alexandra Lambert and Melissa A. Lyle and Priyanka Desai and Chun Liu},
  journal={Experimental Brain Research},
  year={2009},
  volume={201},
  pages={479-488}
}
Brain injury during the last trimester to the first 1–4 years in humans is now thought to trigger an array of intellectual and emotional problems later in life, including disorders such as schizophrenia. In adult schizophrenic brains, there is a specific loss of neurons that co-express glutamic acid decarboxylase-parvalbumin (GAD67-PV). Loss of this phenotype is thought to occur in mature animals previously exposed to N-methyl-d-aspartate receptor (NMDAR) antagonists during late gestation or at… CONTINUE READING