Postnatal development of prefrontal inhibitory circuits and the pathophysiology of cognitive dysfunction in schizophrenia.

Abstract

The typical appearance of the clinical features of schizophrenia during late adolescence or early adulthood suggests that adolescence-related neurodevelopmental events may contribute to the pathophysiology of this disorder. Here the role that GABA-mediated inhibition in the dorsal lateral prefrontal cortex (DLPFC) plays in regulating working memory, a core… (More)

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@article{Lewis2004PostnatalDO, title={Postnatal development of prefrontal inhibitory circuits and the pathophysiology of cognitive dysfunction in schizophrenia.}, author={David Allan Lewis and Dianne A. Cruz and Stephen Eggan and Susan L Erickson}, journal={Annals of the New York Academy of Sciences}, year={2004}, volume={1021}, pages={64-76} }