Postnatal changes to the mechanical properties of articular cartilage are driven by the evolution of its collagen network.

@article{Gannon2015PostnatalCT,
  title={Postnatal changes to the mechanical properties of articular cartilage are driven by the evolution of its collagen network.},
  author={Andy Gannon and Thomas Nagel and Alan P Bell and N C Avery and Daniel J. Kelly},
  journal={European cells & materials},
  year={2015},
  volume={29},
  pages={
          105-21; discussion 121-3
        }
}
While it is well established that the composition and organisation of articular cartilage dramatically change during skeletal maturation, relatively little is known about how this impacts the mechanical properties of the tissue. In this study, digital image correlation was first used to quantify spatial deformation within mechanically compressed skeletally immature (4 and 8 week old) and mature (1 and 3 year old) porcine articular cartilage. The compressive modulus of the immature tissue was… CONTINUE READING
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