Postnatal changes of vascular endothelial growth factor (VEGF) expression in the retinae of normal and hypertensive rats.

@article{Chan2000PostnatalCO,
  title={Postnatal changes of vascular endothelial growth factor (VEGF) expression in the retinae of normal and hypertensive rats.},
  author={Wood-yee Chan and R. Y. S. Cheng and David Tai Wai Yew},
  journal={Life sciences},
  year={2000},
  volume={66 17},
  pages={
          1615-25
        }
}
Vascular endothelial growth factor (VEGF) has been shown to have potent mitotic activity specific to vascular endothelial cells and has been related to vascular permeability, angiogenesis and cell proliferation in both normal and pathological situations. The present study aimed at elucidating the spatio-temporal changes in the postnatal expression pattern of VEGF in the retinae of both normal and hypertensive rats. In situ hybridization with a riboprobe showed that in the pre-hypertensive stage… CONTINUE READING