Postmenopausal status and early menopause as independent risk factors for cardiovascular disease: a meta-analysis.

@article{Atsma2006PostmenopausalSA,
  title={Postmenopausal status and early menopause as independent risk factors for cardiovascular disease: a meta-analysis.},
  author={Femke Atsma and Marie-Louise E L Bartelink and Diederick E. Grobbee and Yvonne T van der Schouw},
  journal={Menopause},
  year={2006},
  volume={13 2},
  pages={265-79}
}
OBJECTIVE Loss of ovarian function and subsequent deficiency of endogenous estrogens is suggested to enhance cardiovascular disease risk and related death after menopause. The aim was to obtain valid estimates of the cardiovascular disease risk associated with postmenopausal status and early menopause. DESIGN A literature search of observational studies was performed using PubMed and EMBASE (1966 to May 1, 2004). Eighteen studies on postmenopausal status and age at menopause in relation to… CONTINUE READING