Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial.

@article{Steiner2005PostmenopausalOE,
  title={Postmenopausal oral estrogen therapy and blood pressure in normotensive and hypertensive subjects: the Estrogen in the Prevention of Atherosclerosis Trial.},
  author={Anne Z. Steiner and Howard N. Hodis and Rog{\'e}rio Souza Lobo and Donna Shoupe and Min Xiang and Wendy J. Mack},
  journal={Menopause},
  year={2005},
  volume={12 6},
  pages={728-33}
}
OBJECTIVE To determine if 17beta-estradiol increases blood pressure in postmenopausal women. DESIGN A total of 222 healthy postmenopausal women were randomly assigned to either 1 mg micronized 17beta-estradiol daily or placebo for 2 years. Blood pressure measurements were obtained every other month and common carotid artery intima-media thickness measured every 6 months. Statistical analyses comparing longitudinal changes in systolic and diastolic blood pressure between treatment groups used… CONTINUE READING