Postmenopausal hormone therapy and breast cancer: what is the problem?

  title={Postmenopausal hormone therapy and breast cancer: what is the problem?},
  author={Peter Kenemans},
  volume={51 1},
Observational studies provide evidence that breast cancer risk is increased with long-term oral use of postmenopausal estrogen replacement therapy (ET). Various large cohort studies have shown that the addition of a progestogen in combined hormone replacement therapy (EPT) increases this risk further. Prospective, randomized controlled trials have confirmed this for the continuous combined regimen. So, why not tell our patients, "Stop using ET and EPT, it is dangerous to your health!"? The… CONTINUE READING

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