Postmenopausal estrogen use, cigarette smoking, and cardiovascular morbidity in women over 50. The Framingham Study.

@article{Wilson1985PostmenopausalEU,
  title={Postmenopausal estrogen use, cigarette smoking, and cardiovascular morbidity in women over 50. The Framingham Study.},
  author={Peter W. F. Wilson and Robert J. Garrison and William Peter Castelli},
  journal={The New England journal of medicine},
  year={1985},
  volume={313 17},
  pages={1038-43}
}
We studied the effect of estrogen use on morbidity from cardiovascular disease in 1234 postmenopausal women, aged 50 to 83 years, participating in the Framingham Heart Study's 12th biennial examination (index examination). The medication history recorded at biennial examinations 8 through 12 was used to classify the degree of estrogen exposure before eight years of observation for cardiovascular morbidity and mortality. Despite a favorable cardiovascular risk profile and control for the major… CONTINUE READING
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