Postmenopausal estrogen and increased risk of clinical osteoarthritis at the hip, hand, and knee in older women.

Abstract

OBJECTIVE We examined postmenopausal estrogen (PME) use and prevalence of clinical osteoarthritis (OA) at the hand, knee, and hip in 1001 community-dwelling postmenopausal women aged 43-97 years (mean age 72). METHODS OA at the hip, hand, and knee was defined by validated and standardized criteria based on pain history plus a clinical examination… (More)

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