Postmenopausal breast cancer and oestrogen associations with the IgA-coated and IgA-noncoated faecal microbiota

@article{Goedert2018PostmenopausalBC,
  title={Postmenopausal breast cancer and oestrogen associations with the IgA-coated and IgA-noncoated faecal microbiota},
  author={James Jerome Goedert and Xing Hua and Agata Bielecka and Isao Okayasu and Ginger L Milne and Gieira S. Jones and Mutsunori Fujiwara and Rashmi Sinha and Yunhu Wan and Xia Xu and Jacques Ravel and Jianxin Shi and Noah W Palm and Heather Spencer Feigelson},
  journal={British Journal of Cancer},
  year={2018},
  volume={118},
  pages={471-479}
}
Background:The diversity and composition of the gut microbiota may affect breast cancer risk by modulating systemic levels of oestrogens and inflammation. The current investigation tested this hypothesis in postmenopausal women by identifying breast cancer associations with an inflammation marker, oestrogen levels, and faecal microbes that were or were not coated with mucosal immunoglobulin A (IgA).Methods:In this population-based study, we compared 48 postmenopausal breast cancer cases (75… CONTINUE READING
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