Postischemic renal injury due to oxygen radicals.

  title={Postischemic renal injury due to oxygen radicals.},
  author={Kamin J. Johnson and Joel M. Weinberg},
  journal={Current opinion in nephrology and hypertension},
  volume={2 4},
Ischemia-reperfusion injury occurs in many organs and is the underlying cause of many disease processes, including myocardial infarction, stroke, and acute renal failure, which in total are responsible for the majority of deaths seen in developed countries. Most of the injury seen with this process is associated with the reperfusion phase in which the blood flow to the ischemic tissues is reinstituted. This reperfusion phase is associated with the formation of reactive oxygen species (ROS) in… CONTINUE READING


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