Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke.

@article{McCullough2001PostischemicER,
  title={Postischemic estrogen reduces hypoperfusion and secondary ischemia after experimental stroke.},
  author={Louise D McCullough and Nabil J. Alkayed and Richard J. Traystman and Melanie J Williams and Patricia D. Hurn},
  journal={Stroke},
  year={2001},
  volume={32 3},
  pages={796-802}
}
BACKGROUND AND PURPOSE Estrogen is a known neuroprotective and vasoprotective agent in experimental cerebral ischemia. Preischemic steroid treatment protects animals of both sexes from focal cerebral ischemia. This study determined whether intravenous estrogen acts as a vasodilator when administered on reperfusion and whether the resulting increase in cerebral blood flow (CBF) provides tissue protection from middle cerebral artery occlusion. METHODS Adult male Wistar rats were treated with… CONTINUE READING
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Effects of estrogen on cerebral blood flow and pial microvasculature in rabbit

  • MT Kearney, DM Agnew, RJ Traystman, PD. Hurn
  • Am J Physiol
  • 2000

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