Postinjury multiple organ failure: role of extrathoracic injury and sepsis in adult respiratory distress syndrome.

@article{Moore1993PostinjuryMO,
  title={Postinjury multiple organ failure: role of extrathoracic injury and sepsis in adult respiratory distress syndrome.},
  author={Fredrick Moore and Ernest Eugene Moore and Rusell Read},
  journal={New horizons},
  year={1993},
  volume={1 4},
  pages={538-49}
}
Adult respiratory distress syndrome (ARDS) and multiple organ failure (MOF) occur as a result of an unbridled systemic inflammatory response (i.e., severe systemic inflammatory response syndrome [SIRS]). Early epidemiologic studies concluded that infection with systemic sepsis was the common pathway for the development of ARDS and eventual MOF. As a consequence, research investigation from 1977 to 1987 focused on later clinical events (e.g., immunosuppression, persistent hypercatabolism, and… CONTINUE READING