Posteroventral medial pallidotomy in advanced Parkinson's disease.

  title={Posteroventral medial pallidotomy in advanced Parkinson's disease.},
  author={Anthony E Lang and Andres M. Lozano and Edna Montgomery and Jane Duff and R. Tasker and Winston L. Hutchinson},
  journal={The New England journal of medicine},
  volume={337 15},
BACKGROUND Posteroventral medial pallidotomy sometimes produces striking improvement in patients with advanced Parkinson's disease, but the studies to date have involved small numbers of patients and short-term follow-up. METHODS Forty patients with Parkinson's disease underwent serial, detailed assessments both after drug withdrawal ("off" period) and while taking their optimal medical regimens ("on" period). All patients were examined preoperatively and 39 were examined at six months; 27 of… CONTINUE READING
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