Posterior lobe of the pituitary in diabetes insipidus: MR findings.


The posterior lobe of the pituitary gland was evaluated by 1.5 T magnetic resonance (MR) in five cases of diabetes insipidus (DI), including one primary (idiopathic) and four secondary DI cases due to germinomas (two), teratoma (one), and histiocytosis X (one). The normal posterior lobe displays high signal indistinguishable from fatty tissue on T1-weighted images (T1WI) (short T1 value). In all five DI cases the normal high signal of the posterior lobe was not detected in the pituitary fossa on T1WI. Hence, because of this characteristic finding, MR may greatly assist in the diagnosis of DI. We may speculate that the short T1 value of the posterior lobe is closely related to its functional integrity and may be due to the neurosecretory materials in the axons of the hypothalamohypophyseal tract.


Citations per Year

3,733 Citations

Semantic Scholar estimates that this publication has 3,733 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Fujisawa1987PosteriorLO, title={Posterior lobe of the pituitary in diabetes insipidus: MR findings.}, author={Ichiro Fujisawa and Kazuo Nishimura and Reinin Asato and K Togashi and Kunihiko Itoh and Satoshi Noma and Yoshiki Kawamura and Tadashi Sago and Saburo Minami and Yoshio Nakano}, journal={Journal of computer assisted tomography}, year={1987}, volume={11 2}, pages={221-5} }