Postconditioning effects of magnesium on cocaine conditioned place preference in mice.

@article{Lawley1990PostconditioningEO,
  title={Postconditioning effects of magnesium on cocaine conditioned place preference in mice.},
  author={Scott I. Lawley and Kathleen Kantak},
  journal={Pharmacology, biochemistry, and behavior},
  year={1990},
  volume={36 3},
  pages={531-8}
}
Magnesium chloride (MgCl2) has recently been shown to have stimulant-like properties. Because stimulants are known to induce conditioned place preference (CPP), the CPP procedure was used to test the hypothesis that cocaine and MgCl2 share similar stimulus properties. This would be shown if cocaine-induced CPP could be enhanced in a postconditioning preference test by MgCl2 and other stimulants. Mice were conditioned with 5.0 mg/kg cocaine to the nonpreferred end of a three-compartment straight… CONTINUE READING

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