Post-treatment of an NADPH oxidase inhibitor prevents seizure-induced neuronal death

  title={Post-treatment of an NADPH oxidase inhibitor prevents seizure-induced neuronal death},
  author={J H Kim and Bong Geom Jang and Bo young Choi and Hyeong Seop Kim and Sang Won Suh},
  journal={Brain Research},
The present study sought to evaluate the neuroprotective effects of apocynin, an NADPH oxidase assembly inhibitor, on seizure-induced neuronal death. Apocynin, also known as acetovanillone, is a natural organic compound isolated from the root of Canadian hemp (Apocynum cannabium). It has been extensively studied to determine its disease-fighting capabilities and application in several brain insults, such as traumatic brain injury and stroke. Here we tested the hypothesis that post-treatment of… CONTINUE READING


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