Post-treatment HIV controllers or spontaneous controllers in disguise?

@article{Wen2017PosttreatmentHC,
  title={Post-treatment HIV controllers or spontaneous controllers in disguise?},
  author={Ying Wen and Jonathan Z. Li},
  journal={AIDS},
  year={2017},
  volume={31 4},
  pages={
          587-589
        }
}
It has been well described that interruption of antiretroviral therapy (ART) leads to rapid viral rebound in the vast majority of HIV-infected individuals, even after prolonged courses of suppressive ART [1]. Yet, intriguingly, a small subset of HIV-infected patients is able to maintain natural control of HIV replication after stopping ART [2,3] and this provides hope that such a goal is attainable in the general population of HIVinfected individuals. Such post-treatment controllers (PTCs) are… 
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jonathanlilab.bwh.harvard.edu
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3 Citations

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Reduce and Control: A Combinatorial Strategy for Achieving Sustained HIV Remissions in the Absence of Antiretroviral Therapy
TLDR
The goal is to devise a safe and effective means for replicating durable post-treatment control on a global scale and to devise methods to reduce the size of the reservoir and to control replication of this residual virus.
The Control of HIV After Antiretroviral Medication Pause (CHAMP) Study: Posttreatment Controllers Identified From 14 Clinical Studies
TLDR
Posttreatment control was more commonly identified amongst early treated individuals, frequently characterized by early transient viral rebound and heterogeneous durability of HIV remission.
HIV control: Is getting there the same as staying there?
TLDR
The natural history of elite and post-treatment control, the evidence from longitudinal studies of controllers who fail and studies of biologic sex, age, and simian immunodeficiency virus (SIV) demonstrate that the battle between the inflammatory and anti-inflammatory pathways during acute infection has long-term consequences.

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