Post-traumatic stress disorder: facts and fiction

  title={Post-traumatic stress disorder: facts and fiction},
  author={Joseph Zohar and Alzbeta Juven-Wetzler and Vicki Myers and Leah Fostick},
  journal={Current Opinion in Psychiatry},
Purpose of review This review provides an update on contemporary perspectives on post-traumatic stress disorder and challenges myths about the disorder and its treatment. Post-traumatic stress disorder has recently attracted public attention because of the impact of international terrorism, although the vast majority of post-traumatic stress disorder cases actually relate to civilian events such as car accidents, rape and violent robbery. This disorder requires deeper understanding and… 

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  • S. Wimalawansa
  • Psychology, Biology
    CNS & neurological disorders drug targets
  • 2014
Among other pathological and biochemical abnormalities, hormonal aberrations are most likely key mechanisms initiating and the maintenance of the PTSD, and neuroendocrine system needs to be considered as a key target for new drug development for prevention and treatment of PTSD.

Propranolol Use in the Prevention and Treatment of Posttraumatic Stress Disorder in Military Veterans: Forgetting Therapy Revisited

  • E. Donovan
  • Psychology
    Perspectives in biology and medicine
  • 2010
If propranolol use in dissociation of emotion and fear from memory is effective in individuals with PTSD, much of the argument against propr ethanol use is moot and the ethical issue is not how treatment may affect them, but whether withholding research and treatment that may alleviate the condition is justifiable.

Trauma- and Stressor-Related Disorders

Posttraumatic stress disorder (PTSD) is a long-lasting debilitating illness with substantial impact on the individual’s work, family, social relations, and quality of life.

Post-Traumatic Stress Disorder and Suicide Risk: A Systematic Review

  • K. KrysińskaD. Lester
  • Psychology
    Archives of suicide research : official journal of the International Academy for Suicide Research
  • 2010
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The Role of Benzodiazepines in the Treatment of Posttraumatic Stress Disorder ( PTSD )

Author’s Address: Nancy C. Bernardy, Ph.D., is affiliated with the National Center for PTSD, Department of Veterans Affairs, White River Junction, VT 05009, and the Department of Psychiatry, Geisel

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The risk of developing PTSD after a traumatic experience depends on several vulnerability factors that may be classified into three distinct categories—pre-traumatic, peri-traumatic, and

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Lifetime prevalence rates for Posttraumatic Stress Disorder (PTSD) are estimated to be 6% in the general population. In the United States alone, an estimated 5.2 million adults will experience PTSD


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Posttraumatic stress disorder: the burden to the individual and to society.

  • R. Kessler
  • Psychology
    The Journal of clinical psychiatry
  • 2000
PTSD is a commonly occurring disorder that often has a duration of many years and is frequently associated with exposure to multiple traumas and is comparable to, or greater than, that of other seriously impairing mental disorders.

An Animal Model of Posttraumatic Stress Disorder: The Use of Cut‐Off Behavioral Criteria

  • H. CohenJ. Zohar
  • Psychology, Biology
    Annals of the New York Academy of Sciences
  • 2004
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Memory of a traumatic event is a strong predictor and a potential risk factor for subsequent development of PTSD and future studies are needed to show whether these findings can be generalized to other traumatic conditions.

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The early administration of benzodiazepines to trauma survivors with high levels of initial distress did not have a salient beneficial effect on the course of their illness, while reducing physiologic expression of arousal.

Natural course of posttraumatic stress disorder: a 20-month prospective study of Turkish earthquake survivors.

Initial PTSD following an earthquake may be as prevalent as in other natural disasters, but high rates of spontaneous remission lead to low prevalence 1.5 years following the earthquake.

Australian Guidelines for the Treatment of Adults with Acute Stress Disorder and Post-Traumatic Stress Disorder

Key recommendations indicate the use of trauma-focused psychological therapy (cognitive behavioural therapy or eye movement desensitization and reprocessing in addition to in vivo exposure) as the most effective treatment for ASD and PTSD.

Posttraumatic stress disorder in the National Comorbidity Survey.

Progress in estimating age-at-onset distributions, cohort effects, and the conditional probabilities of PTSD from different types of trauma will require future epidemiologic studies to assess PTSD for all lifetime traumas rather than for only a small number of retrospectively reported "most serious" traumAs.

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The findings clearly indicate that bodily injury is a major risk factor-rather than a protective one-for PTSD, and suggest that this heightened level of perceived threat is not a simple, straightforward function of the severity of injury or of the traumatic event.

Clarifying the Origin of Biological Abnormalities in PTSD Through the Study of Identical Twins Discordant for Combat Exposure

Analysis of pairs of Vietnam combat veterans and their noncombat‐exposed, identical twins supports the conclusion that the latter abnormalities represent antecedent, familial vulnerability factors for developing chronic PTSD upon exposure to a traumatic event.