Post-traumatic stress disorder, hormones, and memory

  title={Post-traumatic stress disorder, hormones, and memory},
  author={Roger K Pitman},
  journal={Biological Psychiatry},
  • R. Pitman
  • Published 1 July 1989
  • Psychology
  • Biological Psychiatry

Propranolol Degrades Memory Reconsolidation in Conditions of Single and Multiple Combinations of Tones with Pain

It is suggested that the effects of blockade of the noradrenergic system on loss of memory in the reconsolidation stage in these learning models have different mechanisms.

Endocannabinoid Modulation of Predator Stress-Induced Long-Term Anxiety in Rats

The results suggest that predator threat triggers long-term changes in 2-AG-mediated endocannabinoid signaling in the amygdala, and that pharmacological interventions targeting MGL might provide a therapeutic strategy for the treatment of chronic brain disorders initiated by trauma.

Post-Exposure Sleep Deprivation Facilitates Correctly Timed Interactions Between Glucocorticoid and Adrenergic Systems, which Attenuate Traumatic Stress Responses

Intentional prevention of sleep in the early aftermath of stress exposure may well be beneficial in attenuating traumatic stress-related sequelae.

Natural Stressors, Posttraumatic Stress Disorder, and

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Evaluating the effects of stress reduction exercises

Beyond arousal: Prediction error related to aversive events promotes episodic memory formation.

  • F. KalbeL. Schwabe
  • Psychology, Biology
    Journal of experimental psychology. Learning, memory, and cognition
  • 2019
The present data point to prediction error-related learning as a cognitive mechanism that contributes to the emotional enhancement of memory, above and beyond the well-established effects of arousal in emotional memory formation.

PTSD-Like Memory Generated Through Enhanced Noradrenergic Activity is Mitigated by a Dual Step Pharmacological Intervention Targeting its Reconsolidation

These findings highlight the effectiveness of a dual-step pharmacological intervention to mitigate an aberrant and enduring aversive memory similar to that underlying the post-traumatic stress disorder.



A 3-year prospective study of Post-traumatic Stress Disorder in Israeli combat veterans

This study attempted to trace the long-term psychiatric sequelae of combat in a large representative sample of combat stress reaction (CSR) Israeli casualties and matched controls. Employing DSM-III

Cognitive processes and Pavlovian conditioning in humans

A Neo-Pavlovian Interpretation of the OR and Classical Conditioning in Humans: With Comments on Alcoholism and the Poverty of Cognitive Psychology.

Stress-responsive neuromodulators

  • P. Gold
  • Psychology
    Biological Psychiatry
  • 1988

Peripheral and Central Adrenergic Influences on Brain Systems Involved in the Modulation of Memory Storage a

  • J. D. McGaugh
  • Biology, Psychology
    Annals of the New York Academy of Sciences
  • 1985
The current acceleration of interest in animal studies of learning and memory seems to be motivated primarily by interests in understanding human memory and in developing therapy for memory disorders, which is the major concern of the present volume.

Neuropeptides in Human Memory and Learning Processes

The role in human learning of vasopressin, ACTH, and endogenous opioids is still uncertain, although naloxone, which antagonizes their effects, has been associated with improved cognitive performance in patients with Alzheimer's disease.

A neuropsychological hypothesis explaining posttraumatic stress disorders.

  • L. Kolb
  • Psychology, Biology
    The American journal of psychiatry
  • 1987
The author postulates that the "constant" symptoms of the disorder are due to the changes in the agonistic neuronal system which impair cortical control of hindbrain structures concerned with aggressive expression and the sleep-dream cycle.