Post-transplant lymphoproliferative disorder in children: recent outcomes and response to dual rituximab/low-dose chemotherapy combination.

@article{Gupta2010PosttransplantLD,
  title={Post-transplant lymphoproliferative disorder in children: recent outcomes and response to dual rituximab/low-dose chemotherapy combination.},
  author={Sushil K. Gupta and Frederick J Fricker and Regino P. Gonz{\'a}lez-Peralta and William Birdsall Slayton and Pamela M Schuler and Vikas R Dharnidharka},
  journal={Pediatric transplantation},
  year={2010},
  volume={14 7},
  pages={896-902}
}
PTLD is a major complication after transplantation. Treatment options for PTLD are not standardized, usually sequential, starting with reduction in immunosuppression. Recently, we have used a dual combination of rituximab and reduced dose chemotherapy (R/C) directly after failed RI. We retrospectively identified 30 pediatric PTLD cases across four organ systems at our center from 1995 to 2008. We assessed recent outcomes of PTLD in children, comparing the responses to different regimens. Two-yr… CONTINUE READING