Post-translational modifications and protein-specific isoforms in endometriosis revealed by 2D DIGE.

@article{Stephens2010PosttranslationalMA,
  title={Post-translational modifications and protein-specific isoforms in endometriosis revealed by 2D DIGE.},
  author={Andrew N Stephens and Natalie J Hannan and Adam Rainczuk and Katie L Meehan and Jenny C.-Y. Chen and Peter Nicholls and Luk J. F. Rombauts and Peter Gordon Stanton and David M. Robertson and Lois A. Salamonsen},
  journal={Journal of proteome research},
  year={2010},
  volume={9 5},
  pages={2438-49}
}
Endometriosis is a chronic disorder affecting approximately 10% of women in whom endometrial tissue forms painful lesions outside the uterus. It has a major impact on their physical, mental and social well-being but has no known cure, and there is no nonsurgical means of diagnosis. We have used a proteomic approach to identify proteins with altered abundance in the eutopic endometrium of endometriosis patients in the midsecretory phase of the menstrual cycle. 2D-differential in gel… CONTINUE READING
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Menstrual and estrous cycles

  • L. A. Salamonsen
  • The Endometrium . Molecular , Cellular and…
  • 2009

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