Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface.

@article{Solito2006PosttranslationalMP,
  title={Post-translational modification plays an essential role in the translocation of annexin A1 from the cytoplasm to the cell surface.},
  author={Egle Solito and Helen C. Christian and Michela Festa and Abeda Mulla and Tanya Tierney and Roderick John Flower and Julia C. Buckingham},
  journal={FASEB journal : official publication of the Federation of American Societies for Experimental Biology},
  year={2006},
  volume={20 9},
  pages={1498-500}
}
Annexin A1 (ANXA1) has an important role in cell-cell communication in the host defense and neuroendocrine systems. In both systems, its actions are exerted extracellularly via membrane-bound receptors on adjacent sites after translocation of the protein from the cytoplasm to the cell surface of adjacent cells. This study used molecular, microscopic, and pharmacological approaches to explore the mechanisms underlying the cellular exportation of ANXA1 in TtT/GF (pituitary folliculo-stellate… CONTINUE READING

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Modulators of the SUR2B/Kir6.1 ATP-sensitive K channel regulate annexin 1 release in the TtT/GF folliculostellate cell line

  • J. Payne, J. Morris, E. Solito, J. Buckingham
  • 24th Joint Meeting of the British Endocrine…
  • 2005

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