Post-translational modification of tubulin dependent on organelle assembly

  title={Post-translational modification of tubulin dependent on organelle assembly},
  author={Karen J. Brunke and Philip S. Collis and Donald P. Weeks},
Microtubules are involved in a wide variety of cellular functions1–3 and are major components of many subcellular structures (for example, the centriole, mitotic spindle, cytoskeleton and flagellar apparatus). The ability of microtubules to serve in such a diversity of functions may be accounted for, at least in part, by heterogeneity in the constituent types of α- and β-tubulin subunits4–10 in different microtubules. Higher eukaryotes generally possess several tubulin genes and this may… CONTINUE READING

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