Post-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1/punctin-1 by C-mannosylation of tryptophan.

@article{Wang2009PosttranslationalMO,
  title={Post-translational modification of thrombospondin type-1 repeats in ADAMTS-like 1/punctin-1 by C-mannosylation of tryptophan.},
  author={Lauren Weiping Wang and Christina L. Leonhard-Melief and Robert S. Haltiwanger and Suneel S. Apte},
  journal={The Journal of biological chemistry},
  year={2009},
  volume={284 44},
  pages={30004-15}
}
Protein C-mannosylation is the attachment of alpha-mannopyranose to tryptophan via a C-C linkage. This post-translational modification typically occurs within the sequence motif WXXW, which is frequently present in thrombospondin type-1 repeats (TSRs). TSRs are especially numerous in and a defining feature of the ADAMTS superfamily. We investigated the presence and functional significance of C-mannosylation of ADAMTS-like 1/punctin-1, which contains four TSRs (two with predicted C-mannosylation… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 26 extracted citations

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

Matrix biology : journal of the International Society for Matrix Biology • 2015

References

Publications referenced by this paper.
Showing 1-2 of 2 references

hp://w w w .jb.org/ D

Y. Luo, K. Koles, W. Vorndam, R. S. Haltiwanger, V. M. Panin
J Biol Chem 281, • 2006

Enzymatic Digestion of Proteins and HPLC Peptide Isolation. in A Practical Guide to Protein and Peptide Purification for Microsequencing (P

K. L. Stone, K. R. Williams
M. ed.), • 1993

Similar Papers

Loading similar papers…