Post-translational modification of the pyruvate phosphate dikinase from Trypanosoma cruzi.


In kinetoplastids such as Trypanosoma cruzi, glycolysis is compartmentalized in peroxisome-like organelles called glycosomes. Pyruvate phosphate dikinase (PPDK), an auxiliary enzyme of glycolysis, is also located in the glycosomes. We have detected that this protein is post-translationally modified by phosphorylation and proteolytic cleavage. On western… (More)
DOI: 10.1016/j.parint.2013.09.007


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