Post-translational modification of the androgen receptor.

Abstract

Regulation of the androgen receptor (AR) by its cognate ligand is well established, but how post-translational modification modulates AR activity is only emerging. The AR is subject to modification by phosphorylation, acetylation, methylation, SUMOylation, and ubiquitination. As several of the enzymes that modify the AR are altered in prostate cancer… (More)
DOI: 10.1016/j.mce.2011.07.004

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